|
KMID : 0604520070330010047
|
|
Journal of the Society of Cosmetic Scientists of Korea
2007 Volume.33 No. 1 p.47 ~ p.52
|
|
|
A Study on the Antimicrobial Effect of Glyceryl Caprylate in Cosmetics
|
|
Ahn Gi-Woong
Choi Min-Hee
Woo Yun-Taek
Jo Byoung-Kee
|
|
|
Abstract
|
|
|
|
The antimicrobial properties of medium-chain () free fatty acids and their 1-monoglyceride derivatives against a wide range of microorganisms we well known. However, previous studies have been mainly focused on the antimicrobial activity against pathogenic bacteria and viruses causing diseases in human or domestic animals’ infection. But, there have been few reports describing comprehensive surveys of antimicrobial effects against microorganisms in cosmetics. For a start of this study, we evaluated and compared the preservative activities of (glyceryl caprylate) and (glyceryl laurate) 1-monoglyceride in cosmetic formulations. From the result, we found that both of them have very excellent preservative activity against bacteria, but less against fungi. And 1-monoglyceride was a little bit more effective than 1-monoglyceride. According to the test results to evaluate each antimicrobial activity of glyceryl caprylate towards 5 kinds of microorganisms used in preservation efficacy test in cosmetics, gram-positive bacteria S. aureus and yeast C. albicans were sensitive and mold A. niger was most tolerant to glyceryl caprylate. Therefore, we tried to improve the antimicrobial activity of glyceryl caprylate agianst mold such as A. niger so that we could make it used as a preservative for cosmetic products. As a result, we confirmed that the antimicrobial activity of glyceryl caprylate is much improved under acidic conditions in formulation. In addition, we found optimal combinations of glyceryl caprylate with other antimicrobial agents. Among tested 7 antimicrobial agent, methyparaben showed the highest preservative activity in combination with gglyceryl caprylate.
|
|
|
KEYWORD
|
|
|
glyceryl caprylate, antimicrobial, preservative, cosmetics, bacteria
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|